University of South Florida
Tampa, FL
The project focuses on the cellular and molecular mechanisms underlying early blood-brain barrier (BBB) dysfunction in multiple sclerosis (MS). Using a combination of multicellular culture configurations (endothelial cells, astrocytes, pericytes, encephalitogenic T cells, myeloid cells), molecular biology techniques, transgenic BBB-specific knockout/in, and in vivo pathophysiological analyses, the successful candidate will investigate mechanisms of BBB dysfunction in models of MS. The position will be based on 100% research effort. Minimum Qualifications: Doctoral degree from an accredited institution and appropriate experience and training within a selected area of specialization. Must meet university criteria for appointment to the rank of Postdoctoral Fellow. Preferred Qualifications: Strong technical skills and the ability to work independently in core laboratory techniques are essential. These include advanced cell culture, confocal microscopy, immunodetection...