Senior Research Scientist

Senior Research Scientist

Med-Ophthalmology - Pennsylvania-Pittsburgh - (26002108)

The University of Pittsburgh, Ophthalmology Department is searching for a Research Scientist position that will lead the design, production, purification, and quality control of adeno-associated viral (AAV) vectors for in-vitro and in-vivo studies for preclinical and translational projects.

Requirements: • PhD in Molecular Biology, Virology, Cellular Biology

• Hands-on experience with AAV vector production and characterization.

• Proficiency in cell culture, cloning, and viral QC assays.

• Strong organizational, analytical, and communication skills; ability to work independently.

Preferred: • Background in ophthalmology, retinal biology, or neuroscience.

• Familiarity with retinal disease models and ocular vector delivery methods.

• Familiarity with other common molecular biology techniques

Serves as subject matter expert and conducts independent scientific research projects from inception to presentation. Prepares and crafts various complex documentations of research results into manuscripts, proposals, grant applications, and presentations. Trains undergraduates, junior lab members, and research technicians. Manages laboratory policies and coordinates high-level work and project development in collaboration with other specialists.

Essential Functions

• Optimize and scale AAV production, purification, and QC workflows.

• Conduct molecular cloning, transfection, viral packaging, and titration assays (qPCR/ddPCR).

• Collaborate across research teams to design experiments and interpret data.

• Present data during lab and consortium meetings and conferences

• Maintain detailed experimental documentation, SOPs, and safety compliance.

• Mentor junior lab members and participate in lab meetings and publications.

Physical Effort

Ability to sit and stand to perform experiments and to lift up to 20lbs

Assignment Category: Full-time regular

Job Classification: Staff.Senior Research Scientist

Job Family: Research

Job Sub Family: Research Science

Campus: Pittsburgh

Minimum Education Level Required: Professional Doctorate Degree

Minimum Years of Experience Required: 7

Will this position accept substitution in lieu of education or experience: Combination of education and relevant experience will be considered in lieu of education and/ or experience requirement.

Work Schedule: M- F 8:30am to 5:00pm

Work Arrangement: On-Campus: Teams that work on campus, in an office, or in a lab.

Hiring Range: TBD Based Upon Qualifications

Relocation_Offered: No

Visa Sponsorship Provided: Yes

Background Check: For position finalists, employment with the University will require successful completion of a background check

Child Protection Clearances: Not Applicable

Required Documents: Resume

Optional Documents: Not Applicable



Equal employment opportunity, including veterans and individuals with disabilities.

PI283837183