Dana-Farber Cancer Institute
Boston, MA
The lab of Dr. Irene Ghobrial is seeking a highly motivated Postdoctoral Research Fellow to conduct laboratory-based research and lead projects focusing on multiple myeloma and its precursor conditions. Based on the mission of the Ghobrial lab, the successful candidate will be responsible for identifying novel biomarkers for tumor burden, tumor biology, and immune state aiming to improve prognostication and monitoring of therapy response in patients with precursor conditions, including monoclonal gammopathy of unknown significance (MGUS) and smoldering multiple myeloma (SMM). In pursuit of these goals, the successful applicant will leverage next-generation technologies and advanced laboratory methods, including scRNA-seq, single-cell genomic characterization, spatial proteomics/transcriptomics, proteomics, flow sorting, and immunohistochemistry among others. In addition, the application and integration of stat-of-the-art genomic, spatial, and proteomic technologies will be key...