University of Pittsburgh
Pittsburgh, PA
Post Doctoral.Post Doctoral.Associate Med-Ophthalmology - Pennsylvania-Pittsburgh - ( 26004532 ) A highly motivated full-time postdoctoral associate is sought in Dr. Yuanyuan Chen’s laboratory at the Department of Ophthalmology, University of Pittsburgh. The Chen Lab uses pharmacological and molecular biological methods to study retinal degenerative diseases and to find new treatments. Specifically, the Chen Lab is looking for small molecules that upregulate protein homeostasis and those that mitigate retina immune responses. In particular, we use small molecule high-throughput screening, retina ex vivo culture, and in vivo mouse retinal morphology and physiology techniques to identify novel small molecules that repair defective homeostasis observed in cells with mutated rhodopsin. Further, the Chen lab is developing a new drug screening platform using retinal explants to find drugs that prevent retinal degeneration. We aim to discover the most...