Texas Biomedical Research Institute

Texas Biomed is searching for an exceptional postdoctoral scientist to study the consequences of genetic variation in pedigreed primate populations. The position will be based in the Southwest National Primate Research Center (SNPRC) Colony Management Unit, which supports and advises the SNPRC on its nonhuman primate (NHP) genomics resources and research activities. Over the last 55 years, Texas Biomed has developed several large, pedigreed NHP colonies, including baboons, rhesus macaques, and marmosets. Animals within these pedigrees have been extensively characterized at both the genetic and phenotypic levels. The successful applicant will work closely with a team of investigators to conduct population and statistical genetic analyses, support the genetic characterization of NHP colonies, and develop breeding strategies to maintain genetic diversity. THE ROLE: Conduct scientific research under the direct of another scientist with more senior rank. Participate in...

Description: Texas Biomed is searching for Journeyman Plumber to join our Facilities team. The successful candidate will plan and perform installation, preventive maintenance and emergency repairs on plumbing systems. This position will maintain, inspect and certify backflow preventers per the state requirements and assist with boiler repairs as needed.   The Role: Maintain and repair all plumbing components in an industrial environment. Read blueprints and perform pipefitting per drawings and instructions. Repair and replace steam to hot water exchangers for very large heated washers. Repair and replace pneumatic steam valves, radiator valves, traps, and steam and condensate pipes. Remove, repair/arrange for repair, and replace domestic hot water heat pumps, chilled water pumps, sump pumps, sewage pumps, lift station pumps, etc. Troubleshoot and repair piping and valves to autoclaves, boilers, cage washer systems and other equipment as needed. Who We Are:  Join...

Description: We're seeking an enthusiastic and proactive Laboratory Assistant (Part-Time) to support research investigating the fundamental molecular mechanisms of Ebola and Marburg virus replication and the development of new antivirals. This position combines hands-on laboratory work, maintaining laboratory supplies and equipment, preparing reagents, managing inventory and documentation, coordinating routine administrative tasks, and supporting research activities.  This is a part-time position scheduled for 20 hours per week. JOB DUTIES:  Responsibilities include supporting research on virus-host interactions and antiviral development as well as providing basic lab maintenance support as outlined below:  • Assist in the isolation of human cells.  • Perform routine laboratory techniques appropriate to experience level, which may include cell culture, microscopy, and Western blotting.  • Maintain accurate research and laboratory records.  • Prepare culture...

Description: We are seeking a highly motivated Postdoctoral Scientist to join our team investigating the gut-brain axis, intestinal inflammation and neuroinflammation in HIV/SIV infection. This role focuses on studying epigenetic changes in discrete colon enterocyte populations and characterizing the viral reservoir in simian immunodeficiency virus (SIV)-infected macaques receiving suppressive antiretroviral therapy (ART) and orally administered minor cannabinoids. This position offers the opportunity to learn and apply novel tools to study epigenetic mechanisms, utilize advanced PET/CT and MRI imaging modalities, and evaluate innovative nanodelivery vehicles for cannabinoid administration in the rhesus macaque model. Our laboratory is pursuing several exciting research initiatives, including: Epigenetic Regulation of the Gut-Brain Axis : Investigating epigenetic mechanisms regulating chronic intestinal inflammation, fibrosis, dysbiosis, and subsequent neuroinflammation via...

Description: We are seeking a detail-oriented and highly motivated Research Associate to support innovative research focused on host-pathogen interactions using the simian immunodeficiency virus (SIV) rhesus macaque model. In this role, you will provide critical laboratory and data management support for multiple NIH-funded HIV/AIDS research projects investigating viral persistence, immune responses, transcriptomic, metabolomic and epigenetic changes and neurocognitive disease. The successful candidate will prepare and process blood and tissue samples for molecular and cellular analyses, perform a wide range of immunology and molecular biology techniques, maintain valuable biorepositories, and collaborate closely with a multidisciplinary research team.    THE ROLE: Prepare blood and tissue samples for nucleic acid extraction, including DNA, total RNA, microRNA, and long non-coding RNA (lncRNA) analyses. Perform total RNA extraction for gene expression, DNA methylation, and...

Description: Texas Biomed is searching for a Veterinary Research Technician – Macaque group to join our team. This position will provide support and technical assistance on research, clinical, and surgical procedures with the Macaque group. The Role: Performs observations of laboratory non -human primates in single and group housing and provides husbandry care Reviews clinical history, and performs a basic health check. Triages and aids in the treatment of animals with wounds and other clinical conditions under the direction of a Veterinarian. Uses appropriate standard husbandry procedures to clean and sanitize animal areas. Prepares, induces, maintains, recovers, and documents anesthesia events to include IV catheterization and intubation. Collects, labels, and distributes biological specimens and tissues from non-human primates. Maintains, cleans, operates, and reports condition of equipment. Prepares non-human primates for pathologic evaluation and may assist...

Description: Texas Biomed is searching for a Veterinary Research Technician to join our team. This position will provide support and technical assistance on research, clinical, and surgical procedures with non-human primates in Animal Biosafety Level 2 (ABSL2) and Animal Biosafety Level 3 (ABSL3) facilities. The Role: Animal Observations and Clinical Care: • Performs observations of laboratory non-human primates in single and group housing and provides husbandry care • Reviews clinical history, and performs a basic health check. • Triages and aids in the treatment of animals with wounds and other clinical conditions under the direction of a Veterinarian. • Uses appropriate standard husbandry procedures (ABSL2 and ABSL3) to clean and sanitize animal areas. Research Support: • Prepares, induces, maintains, recovers, and documents basic anesthesia events to include IV catheterization and intubation. • Collects, label, and distributes biological specimens and tissues from...