Associate Scientist 1 - Strain & Enzyme Engineering.

  • Amyris, Inc.
  • Emeryville, CA, USA
  • Sep 19, 2019

Job Description

Amyris, Inc.

Location: Emeryville, CA
Team: Research and Development - Biology
Work Type: Full-Time

Amyris, a leader in industrial synthetic biology, uses its innovative bioscience solutions to achieve renewable products by converting plant sugars into hydrocarbon molecules. Amyris’ molecules are used in wide range of specialty & performance chemicals, flavors & fragrances and in applications ranging from cosmetics to biofuels. Learn more at

As a VEVRAA Federal Contractor, Amyris is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, sex, color, religion, sexual orientation, gender identity, national origin, disability status, protected veteran status, or any other characteristic protected by law. Amyris complies with applicable state and local laws governing nondiscrimination in employment.

For a full list of our current openings, please visit our website

Amyris is seeking an Associate Scientist with a background in biochemistry, microbiology, synthetic biology, chemistry or chemical engineering, and with substantial experience in molecular biology techniques. Working with a team of scientists and utilizing the world's most advanced high-throughput automated strain engineering platform, the successful candidate will design, build, and test microbial strains and enzymes to improve strain performance (i.e., conversion of sugar into target molecules) in industrial fermentation conditions.

    • Learn and use in-house computational tools to translate hypotheses and metabolic pathways into multi-component DNA designs and genetically complex microbial strains.
    • Create and test large libraries of natural and engineered enzymes.
    • Work with the automated strain engineering, high-throughput screening, analytical chemistry, systems biology, and fermentation groups to build and test engineered strains in concurrent, overlapping experiments.
    • Implement and troubleshoot molecular biology protocols for work with yeast, bacteria, and isolated DNA.
    • Keep thorough and careful notes on all lab work and samples.
    • Analyze experimental results to draw well-supported conclusions and generate hypotheses.
    • Communicate scientific results within the team and to small audiences.
    • Troubleshoot and improve processes to increase efficiency, speed, and efficacy.

    • B.S. degree in molecular biology, biochemistry, genetics, molecular biology, chemistry, chemical engineering, or a related discipline
    • Strong background in molecular biology techniques including PCR, multi-part DNA assembly, nuclease-assisted transformations, DNA sequencing, microbial transformations, and live cell cultivation
    • Excellent laboratory skills to generate high quality, reproducible data and independently troubleshoot when needed
    • Experience with DNA sequence analysis and in silico DNA sequence manipulation
    • Proficiency with Microsoft Excel (or R or similar programs) and comfortable with analysis of large data sets using a variety of software tools
    • Ability to handle multiple independent experiments in a staggered and concurrent fashion
    • Effective written and verbal communication
    • Track record of successful work on a team

Optional favorable characteristics
    • Experience with S. cerevisiae
    • Knowledge of SQL or other database tools and/or a basic proficiency with Python or other programming language
    • iGEM experience
    • Deep knowledge of metabolic pathways, natural products chemistry, or laboratory directed evolution
    • Experience with protein evolution, engineering, structural analysis, and/or kinetic measurements